USP/Bp Product Promote Drug Dissolution Low Substituted Hyposubstituted Hydroxypropyl Cellulose Powder

• CAS No.: 9004-64-2
• Formula: /
• EINECS: /
• Model NO.: L-HPC H-HPC
• Type: Pharma Ingredients
• Appearance: Powder
• Quality: Refined
• Colour: White
• Transport Package: 20kg/Drum
• Trademark: Forta
• Origin: China
• HS Code: 39129000
• Production Capacity: 2000tons/Year

Product Description

                                                Hydroxypropyl cellulose(HPC)

       High Substitution Hydroxypropyl cellulose(H-HPC)                                       Low Substitution Hydroxypropyl cellulose(L-HPC)

   Product Characteristics                                                                                 Product Characteristics
  1.Out looking: H-HPC is a white or lightly white powder, odorless                      1. Out looking: L-HPC is a white or light gray mobile power with               and tasteless.                                                                                                       odorless and tasteless.
  2.Pellet: 20 screen passable rate is over 99%, 30 screen passable rate is        2.Solubility: does not dissolve in waterless ethanol, aether or  
     95%.                                                                                                                    acetone. dissolves in water to clear or slightly turgidity colloid         3.Fault sepcific gravity:0.50-0.60g/cm³,gravity: 1.2224g/cm³                               solution.  It can dissolve in some organic solvents or some water    4.Thermo stability:                                                                                                  Components.
      Temperature at which color change: 195~210ºC.                                            3. Dispensation change: L-HPC can not be dispense with other
       Carbonization temperature:260~275ºC.                                                          high density electrolytes,otherwise may cause salt out.Dissolved
       Intenerate point:130ºC                                                                                    L-HPC and phenol derivatives such as methyl & propyl may cause           At temperature low than 38ºC, becomes clear and transparent solution in    some abstain from contraindication to hydroxy benzyl acids.
       water.
      Gelatin temperature: over 40ºC.

Properties--H-HPC
 

1. At normal temperature, it can dissolve it in many kinds of liquids such as absolute ethyl carbinol, alcohol, isopropyl, dichloride-methane, as well as in acetone, chloroform and acid solution agent. All solution are clear and transparent.
2. H-HPC is good thermoplastic material with excellent film forming ability. Film formed using H-HPC is very rigid with good polish and high elasticity.
3. Low content of ash presents result excellent adhesive. It can be used as adhesive agent for latex, stable with good dispersing ability.
4. H-HPC is not a drug itself, poison less and has no physiological effect.
5. H-HPC possesses good chemical inertia, hardly to react with other chemicals.
6. The substitute base is distributed uniformly and sufficiently thus H-HPC is powerful in antibacterial.
7. Low content of balance moisture.
8. H-HPC does not become gelatin in acid solution due to its non-ionic composition and in large range of PH solution, its presents excellent stability.
9. Solution of H-HPC can form regular liquid crystal of tropism.
10. Solution of H-HPC possesses surface activity.
11. With temperature rising and down, solution of H-HPC can change from gelatin to solution which is.

 

Properties--L-HPC

1. L-HPC is mainly for application of chemicals as adhesive agent and crack agent forming agent to improve hardness crack ability increasing freedom of release as well as improve inner quality and curative effect. Especially for some big fragile tablets with high elasticity, L-HPC can improve the hardness and finishes as well as make the tablets swiftly crack. Even if the hardness is 13kg, crack only need about 10 minutes.
2. Add 5-20% percent when make tablets adhesives using wet method. Direct usage can be 5-20%   when directly form tablets, when used as tablet crack agent, it shall be 2-10% dosage. Normally, use 5% both inside and outside according to certain prescription.
3. L-HPC is also used as additives for foodstuff as emulsification, stabilizing agent, suspending agent, thicker agent, coating agent for drinks, cakes ,jams, etc.
   4.L-HPC is also used in daily chemicals when making frost agent, shampoo, emulsion, etc.

Specification of Product H-HPC

Item	Standard
Methoxyl content, %	60.0~66.0
PH	5.0~8.0
Loss on drying,%	5.0 max
Residue on ignition,%	0.2 max
Lead, ppm	10 max
Heavy metals, ppm	20 max
Viscosity, mPa.s	In accordance with the viscosity specification as shown in table 2.

Viscosity specification    
                                           

Grade	Viscosity  mP.s
M	4000~6500  at 2%
G	150~400   at 2%
J	150~400   at 5%
L	75~150    at 5%

Specification of Product L-HPC

Item	Standard
Methoxyl  content, %	7.0~16.0
PH	5.0~7.5
Chloride,%	0.2 max
Loss on drying,%	8.0 max
Residue on ignition,%	1.0 max
Iron,ppm	10 max
Heavy metals,ppm	20 max
Arsenic,ppm	3 max

Common Type

Type	Hydroxypropoxy Content,%	Average Particle Size
LH-11	10-12.9	50
LH-21	10-12.9	40
LH-22	7-9.9	40

Factory View


             
Hydroxypropyl cellulose(HPC) Package     20KG/drum or according to customer's request